Maintained at the University of Iowa and developed by U.S. Public Health Services. The Handbook is designed to provide primary care clinicians with a practical and comprehensive reference on clinical preventive services, including screening tests for the early detection of disease, immunizations and prophylaxis to prevent disease, and counseling to modify risk factors that lead to disease.

The new author team of the Fourth Edition provides a student-friendly approach to the subject while offering cutting-edge coverage of new discoveries and concepts in this rapidly evolving field. The ever-increasing impact of immunology on modern medical practice is reflected, with enhanced emphasis on clinical aspects of immunology.

The National Immunization Program (NIP) is a part of the Centers for Disease Control and Prevention, located in Atlanta, Georgia. As a disease-prevention program, NIP provides leadership for the planning, coordination, and conduct of immunization activities nationwide.